Mayim Bialik details extensive side effects from GLP-1 injections

Mayim Bialik suffered “explosive, uncontrollable diarrhoea” and other side effects after being prescribed weight loss injections.

Mayim Bialik suffered “explosive, uncontrollable diarrhoea” after being prescribed weight loss injections.

The former Big Bang Theory actress was advised to try “one shot of the lowest dose of a synthetic GLP-1″ in a bid to tackle the symptoms of various autoimmune conditions she suffers from, but experienced a wide range of negative side effects.

In an essay for The Free Press titled My GLP-1 Nightmare, Mayim wrote: “[I experienced] explosive, uncontrollable diarrhoea. Sulfur burps so violent, they left me afraid to open my mouth in public.

“Sneezing attacks every time I tried to eat or drink—which apparently has a name: snatiation.

“Cramping. Bloating. Full-body aching, as though I had the flu. And an inability to keep down even small sips of water without sprinting to the bathroom with yet more explosive diarrhoea. More than three times, I didn’t make it.

“To say I had an adverse reaction would be somewhat of an understatement.”

The 50-year-old star sought advice from a gastroenterologist, who reassured her the “dramatic” symptoms were not unusual.

She wrote: “These medications, he said, are extremely disruptive to the body and should not be used outside of a specific, regulated set of serious medical reasons—namely, life-compromising obesity and its related health consequences. I did not meet that bar.”

The doctor also suggested other medications the Blossom actress was taking may have contributed to the side effects.

Mayim was diagnosed with Graves’ disease at the age of 23 and later also told she had connective tissue disease, mast cell activation syndrome (MCAS), Sjögren’s syndrome and dysautonomia.

And as a result, the actress – who has Miles, 18, and 15-year-old Frederick with ex-husband Michael Stone – was prescribed the weight loss drug after “a doctor told me it might help ease symptoms I’ve struggled with for basically my entire adult life.”

She wrote: “A few months ago, three separate doctors all suggested I try a GLP-1.

“Not because of the 20 postmenopausal pounds but because the drugs have shown promise in reducing the systemic inflammation that drives autoimmune conditions.”

But despite her own experiences of the drugs not being the “magic cure” she had hoped for, the Jeopardy! presenter insisted they aren’t all bad.

She wrote: “GLP-1s have helped people in serious need. Of that I am certain. But nobody talks much about what happens when it goes wrong.”